Imagine a warm bowl of soup, filled with comforting flavors and a promise of healing. Italian Penicillin Soup is a traditional dish passed down through generations, revered for its medicinal qualities and rich taste. The origins of this dish are rooted in the Italian countryside, where families have relied on it to help fight off colds and flu for centuries. This hearty soup is typically made with simple yet powerful ingredients like chicken, garlic, herbs, and vegetables, all of which come together to create a nourishing meal that also doubles as a natural remedy.
Why It’s Called ‘Penicillin Soup’
The name “Penicillin Soup” might raise a few eyebrows. It’s not because the soup contains any actual antibiotics, but because of its remarkable ability to soothe and heal. This soup has long been considered an effective remedy for common colds and flu. Its garlic content, known for its antimicrobial properties, alongside chicken and herbs, gives the soup a reputation for fighting off illness in a way that’s both comforting and natural. Over time, it’s become a staple dish that people turn to when they need a little extra help from Mother Nature.
The Health Benefits of Italian Penicillin Soup
A Natural Remedy for Colds and Flu
Italian Penicillin Soup isn’t just good for the soul, it’s also great for your body. The combination of chicken and garlic in this soup has long been celebrated for its health benefits. Chicken provides protein and essential vitamins that help boost the immune system, while garlic is known for its antibacterial and antiviral properties. Together, these ingredients help combat infections and strengthen the body’s defenses against common illnesses like the flu and colds.
The herbs used in the soup—such as thyme, rosemary, and sage—are also packed with antioxidants that support the immune system. Whether you’re feeling run-down or fighting off a seasonal illness, a bowl of this soup can give your body the support it needs to recover quickly.
Nutrient-Rich and Soul-Soothing
Beyond its healing properties, Italian Penicillin Soup is also loaded with nutrients that promote overall health. The vegetables in the soup, including carrots, onions, and celery, provide fiber, vitamins, and minerals that contribute to digestive health and enhance the body’s ability to absorb nutrients. Meanwhile, the chicken adds a good amount of protein, which is vital for repairing tissues and maintaining muscle mass.
The best part? It’s soul-soothing. There’s something incredibly comforting about a warm bowl of soup on a cold day or when you’re feeling under the weather. It’s a dish that’s both nourishing and emotionally satisfying.

How to Make Italian Penicillin Soup
Ingredients
To make this soul-soothing soup, gather these ingredients:
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2 tablespoons olive oil
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1 medium onion, chopped
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3 cloves garlic, minced
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2 large carrots, diced
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2 celery stalks, diced
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1 small zucchini, diced
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1 medium potato, peeled and diced
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6 cups chicken broth (preferably homemade or low sodium)
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1 pound chicken breast, boneless and skinless
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1/2 cup small pasta (like orzo or ditalini)
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1 teaspoon dried oregano
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1 teaspoon dried thyme
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1 bay leaf
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Salt and pepper, to taste
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Fresh parsley, chopped (for garnish)
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Parmesan cheese, grated (optional, for serving)
Step-by-Step Guide
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Prepare the ingredients: Start by chopping your vegetables and mincing the garlic. Set them aside for later use.
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Cook the chicken: In a large pot or Dutch oven, heat 1 tablespoon of olive oil over medium-high heat. Season the chicken breasts with salt and pepper, and cook them for about 6-7 minutes on each side until golden brown. Remove from the pot and set aside to cool.
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Sauté the aromatics: In the same pot, add another tablespoon of olive oil. Sauté the onion, garlic, carrots, celery, zucchini, and potato for about 5 minutes until the vegetables soften and become aromatic.
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Add the broth: Pour in the chicken broth, and add the dried oregano, thyme, and bay leaf. Stir everything together and bring the mixture to a boil.
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Shred the chicken: While the soup is heating, shred the cooked chicken using two forks. Add the shredded chicken back into the pot.
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Simmer the soup: Reduce the heat to low and let the soup simmer for about 20 minutes. This allows all the flavors to meld together beautifully.
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Cook the pasta: Add the pasta to the pot and cook for another 8-10 minutes, or until the pasta is tender.
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Final touches: Taste the soup and adjust seasoning with additional salt and pepper if needed. Remove the bay leaf.
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Serve: Ladle the soup into bowls, garnish with fresh parsley, and sprinkle with grated Parmesan cheese, if desired.
Variations of Italian Penicillin Soup
Regional Differences in Ingredients and Preparation
While Italian Penicillin Soup follows a general template, each region in Italy has its own take on the recipe. In southern Italy, for example, the soup might include a dash of spicy red pepper, which adds a kick and helps clear nasal passages. In the northern regions, you might find a version that incorporates more creamy elements or even different types of poultry, such as turkey.
The variations aren’t just about the ingredients, though. The preparation method can also differ. In some areas, the soup is simmered for hours to extract every bit of flavor from the ingredients, while in others, it’s cooked more quickly to retain the freshness of the vegetables. Regardless of the region, each version of Italian Penicillin Soup carries the same comforting, healing qualities.
Vegan or Vegetarian Versions
If you’re looking for a plant-based version of Italian Penicillin Soup, you’re in luck. The great thing about this dish is that it’s easy to adapt without compromising on flavor. For a vegan twist, swap the chicken for a hearty combination of vegetables like mushrooms, lentils, or beans. These plant-based ingredients provide a similar richness and substance while still offering the nourishing benefits that the traditional recipe provides.
Garlic, onions, and herbs still take center stage, ensuring that the soup remains flavorful and aromatic. To add a bit of heartiness, you can also toss in some pasta or quinoa for added texture. This vegan version is just as comforting and immune-boosting as the original, proving that you don’t need meat to enjoy the benefits of Penicillin Soup.

How to Serve and Pair Italian Penicillin Soup
Ideal Side Dishes and Beverages
Italian Penicillin Soup is a meal in itself, but there are plenty of side dishes and beverages that can complement its comforting qualities. A simple side salad with a light vinaigrette can provide a refreshing contrast to the rich flavors of the soup. You might also enjoy some crusty bread on the side, perfect for dipping into the savory broth.
As for beverages, a glass of white wine pairs wonderfully with this soup, particularly something light and crisp like Pinot Grigio or Verdicchio. If you prefer a non-alcoholic option, a warm herbal tea or even a fresh fruit juice can make a refreshing and complementary choice.
Best Time to Enjoy Italian Penicillin Soup
This soup shines during cold winter months or when you’re feeling under the weather. Its warmth and soothing properties make it the perfect comfort food for chilly days. It’s especially helpful when you have a cold or flu, as it helps clear your sinuses and provides your body with the nutrients it needs to heal.
But you don’t need to be sick to enjoy this soup. It’s also great as a quick and comforting meal after a long day or as a cozy dinner on a cold evening. It’s the kind of dish that brings people together, whether you’re fighting off an illness or simply enjoying a hearty meal with loved ones.
Storing and Reheating Italian Penicillin Soup
Proper Storage Techniques
Leftovers? No problem. Italian Penicillin Soup stores well and can be enjoyed over several days. To keep it fresh, simply let the soup cool to room temperature before transferring it to an airtight container. Store it in the fridge for up to 3-4 days. If you need to store it for longer, you can freeze the soup for up to three months. When freezing, make sure to leave a little space in the container for the soup to expand as it freezes.
Reheating Tips
When you’re ready to enjoy your leftovers, reheating the soup is easy. Gently warm it on the stove over low to medium heat, stirring occasionally to prevent it from sticking. If the soup has thickened too much in the fridge, you can add a splash of broth or water to loosen it up.
Alternatively, you can reheat individual portions in the microwave. Just be sure to stir it well before serving, so the heat is evenly distributed. The soup will taste just as good as it did when it was first made.
Final Thoughts
Italian Penicillin Soup is not only a remedy for a cold but a delightful, nourishing meal that everyone can enjoy. By combining fresh, wholesome ingredients with aromatic spices, this soup delivers the comfort and care you need on a chilly day or when feeling under the weather.
With its easy preparation and delicious flavors, it’s the perfect dish to share with family and friends. So, why not make a big batch today? You’ll be sipping and savoring every spoonful!